Estronex Test: the body metabolizes estrogens into several different metabolites that can impact cancer development. One metabolite, 2-hydroxyestrone (2-OHE1), tends to inhibit cancer growth. Another, 16-a-hydroxyestrone (16-a-OHE1), actually encourages tumor development. A woman’s "biochemical individuality" determines which of these metabolites predominates. An Estronex 2/16 ratios less than 2.0 indicates increasing long-term risk for breast, cervical, and other estrogen-sensitive cancers. Importantly, nutritional interventions can help raise Estronex 2/16 ratios and decrease long-term risk.